Barriers to living donor kidney transplantation in the United Kingdom: A national observational study

Diana A. Wu; Matthew L. Robb; Christopher J.E. Watson; John L.R. Forsythe; Charles R.V. Tomson; John Cairns; Paul Roderick; Rachel J. Johnson; Rommel Ravanan; Damian Fogarty; Clare Bradley; Andrea Gibbons; Wendy Metcalfe; Heather Draper; Andrew J. Bradley; Gabriel C. Oniscu

doi:10.1093/ndt/gfx036

Barriers to living donor kidney transplantation in the United Kingdom: A national observational study

Diana A. Wu, Matthew L. Robb, Christopher J.E. Watson, John L.R. Forsythe, Charles R.V. Tomson, John Cairns, Paul Roderick, Rachel J. Johnson, Rommel Ravanan, Damian Fogarty, Clare Bradley, Andrea Gibbons, Wendy Metcalfe, Heather Draper, Andrew J. Bradley, Gabriel C. Oniscu

Psychology (PSY)

Research output: Contribution to journal › Article › peer-review

45 Downloads (Pure)

Abstract

Background. Living donor kidney transplantation (LDKT) provides more timely access to transplantation and better clinical outcomes than deceased donor kidney transplantation (DDKT). This study investigated disparities in the utilization of LDKT in the UK. Methods. A total of 2055 adults undergoing kidney transplantation between November 2011 and March 2013 were prospectively recruited from all 23 UK transplant centres as part of the Access to Transplantation and Transplant Outcome Measures (ATTOM) study. Recipient variables independently associated with receipt of LDKT versus DDKT were identified. Results. Of the 2055 patients, 807 (39.3%) received LDKT and 1248 (60.7%) received DDKT. Multivariable modelling demonstrated a significant reduction in the likelihood of LDKT for older age {odds ratio [OR] 0.11 [95% confidence interval (CI) 0.08-0.17], P

Original language	English
Pages (from-to)	890-900
Number of pages	11
Journal	Nephrology Dialysis Transplantation
Volume	32
Issue number	5
DOIs	https://doi.org/10.1093/ndt/gfx036
Publication status	Published - 1 May 2017

Keywords

inequity
kidney transplantation
living donor
preemptive transplantation
sociodemographic disparities
2020

Access to Document

10.1093/ndt/gfx036

Wu et al. NDT 2017Final published version, 1.12 MBLicence: CC BY

Cite this

Wu, D. A., Robb, M. L., Watson, C. J. E., Forsythe, J. L. R., Tomson, C. R. V., Cairns, J., Roderick, P., Johnson, R. J., Ravanan, R., Fogarty, D., Bradley, C., Gibbons, A., Metcalfe, W., Draper, H., Bradley, A. J., & Oniscu, G. C. (2017). Barriers to living donor kidney transplantation in the United Kingdom: A national observational study. Nephrology Dialysis Transplantation, 32(5), 890-900. https://doi.org/10.1093/ndt/gfx036

Wu, Diana A. ; Robb, Matthew L. ; Watson, Christopher J.E. ; Forsythe, John L.R. ; Tomson, Charles R.V. ; Cairns, John ; Roderick, Paul ; Johnson, Rachel J. ; Ravanan, Rommel ; Fogarty, Damian ; Bradley, Clare ; Gibbons, Andrea ; Metcalfe, Wendy ; Draper, Heather ; Bradley, Andrew J. ; Oniscu, Gabriel C. / Barriers to living donor kidney transplantation in the United Kingdom: A national observational study. In: Nephrology Dialysis Transplantation. 2017 ; Vol. 32, No. 5. pp. 890-900.

@article{8d15417676ce4f78b91b64966ab27ad9,

title = "Barriers to living donor kidney transplantation in the United Kingdom: A national observational study",

abstract = "Background. Living donor kidney transplantation (LDKT) provides more timely access to transplantation and better clinical outcomes than deceased donor kidney transplantation (DDKT). This study investigated disparities in the utilization of LDKT in the UK. Methods. A total of 2055 adults undergoing kidney transplantation between November 2011 and March 2013 were prospectively recruited from all 23 UK transplant centres as part of the Access to Transplantation and Transplant Outcome Measures (ATTOM) study. Recipient variables independently associated with receipt of LDKT versus DDKT were identified. Results. Of the 2055 patients, 807 (39.3%) received LDKT and 1248 (60.7%) received DDKT. Multivariable modelling demonstrated a significant reduction in the likelihood of LDKT for older age {odds ratio [OR] 0.11 [95% confidence interval (CI) 0.08-0.17], P",

keywords = "inequity, kidney transplantation, living donor, preemptive transplantation, sociodemographic disparities, 2020",

author = "Wu, {Diana A.} and Robb, {Matthew L.} and Watson, {Christopher J.E.} and Forsythe, {John L.R.} and Tomson, {Charles R.V.} and John Cairns and Paul Roderick and Johnson, {Rachel J.} and Rommel Ravanan and Damian Fogarty and Clare Bradley and Andrea Gibbons and Wendy Metcalfe and Heather Draper and Bradley, {Andrew J.} and Oniscu, {Gabriel C.}",

year = "2017",

month = may,

day = "1",

doi = "10.1093/ndt/gfx036",

language = "English",

volume = "32",

pages = "890--900",

journal = "Nephrology Dialysis Transplantation",

issn = "0931-0509",

publisher = "Oxford University Press",

number = "5",

}

Wu, DA, Robb, ML, Watson, CJE, Forsythe, JLR, Tomson, CRV, Cairns, J, Roderick, P, Johnson, RJ, Ravanan, R, Fogarty, D, Bradley, C, Gibbons, A, Metcalfe, W, Draper, H, Bradley, AJ & Oniscu, GC 2017, 'Barriers to living donor kidney transplantation in the United Kingdom: A national observational study', Nephrology Dialysis Transplantation, vol. 32, no. 5, pp. 890-900. https://doi.org/10.1093/ndt/gfx036

Barriers to living donor kidney transplantation in the United Kingdom: A national observational study. / Wu, Diana A.; Robb, Matthew L.; Watson, Christopher J.E.; Forsythe, John L.R.; Tomson, Charles R.V.; Cairns, John; Roderick, Paul; Johnson, Rachel J.; Ravanan, Rommel; Fogarty, Damian; Bradley, Clare; Gibbons, Andrea; Metcalfe, Wendy; Draper, Heather; Bradley, Andrew J.; Oniscu, Gabriel C.

In: Nephrology Dialysis Transplantation, Vol. 32, No. 5, 01.05.2017, p. 890-900.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Barriers to living donor kidney transplantation in the United Kingdom: A national observational study

AU - Wu, Diana A.

AU - Robb, Matthew L.

AU - Watson, Christopher J.E.

AU - Forsythe, John L.R.

AU - Tomson, Charles R.V.

AU - Cairns, John

AU - Roderick, Paul

AU - Johnson, Rachel J.

AU - Ravanan, Rommel

AU - Fogarty, Damian

AU - Bradley, Clare

AU - Gibbons, Andrea

AU - Metcalfe, Wendy

AU - Draper, Heather

AU - Bradley, Andrew J.

AU - Oniscu, Gabriel C.

PY - 2017/5/1

Y1 - 2017/5/1

N2 - Background. Living donor kidney transplantation (LDKT) provides more timely access to transplantation and better clinical outcomes than deceased donor kidney transplantation (DDKT). This study investigated disparities in the utilization of LDKT in the UK. Methods. A total of 2055 adults undergoing kidney transplantation between November 2011 and March 2013 were prospectively recruited from all 23 UK transplant centres as part of the Access to Transplantation and Transplant Outcome Measures (ATTOM) study. Recipient variables independently associated with receipt of LDKT versus DDKT were identified. Results. Of the 2055 patients, 807 (39.3%) received LDKT and 1248 (60.7%) received DDKT. Multivariable modelling demonstrated a significant reduction in the likelihood of LDKT for older age {odds ratio [OR] 0.11 [95% confidence interval (CI) 0.08-0.17], P

AB - Background. Living donor kidney transplantation (LDKT) provides more timely access to transplantation and better clinical outcomes than deceased donor kidney transplantation (DDKT). This study investigated disparities in the utilization of LDKT in the UK. Methods. A total of 2055 adults undergoing kidney transplantation between November 2011 and March 2013 were prospectively recruited from all 23 UK transplant centres as part of the Access to Transplantation and Transplant Outcome Measures (ATTOM) study. Recipient variables independently associated with receipt of LDKT versus DDKT were identified. Results. Of the 2055 patients, 807 (39.3%) received LDKT and 1248 (60.7%) received DDKT. Multivariable modelling demonstrated a significant reduction in the likelihood of LDKT for older age {odds ratio [OR] 0.11 [95% confidence interval (CI) 0.08-0.17], P

KW - inequity

KW - kidney transplantation

KW - living donor

KW - preemptive transplantation

KW - sociodemographic disparities

KW - 2020

UR - https://www.mendeley.com/catalogue/bd1b28f4-0a62-3230-9add-aa8d167d829e/

U2 - 10.1093/ndt/gfx036

DO - 10.1093/ndt/gfx036

M3 - Article

C2 - 28379431

VL - 32

SP - 890

EP - 900

JO - Nephrology Dialysis Transplantation

JF - Nephrology Dialysis Transplantation

SN - 0931-0509

IS - 5

ER -

Barriers to living donor kidney transplantation in the United Kingdom: A national observational study

Abstract

Keywords

Access to Document

Other files and links

Cite this